Current Projects

Title: The Impact of Consumption of Eggs in the Context of Plant-Based Diets on Endothelial Function, Diet Quality, and Cardio-Metabolic Risk Factors in Adults at Risk for Type 2 Diabetes
Status: Current
Topic: Cardiovascular Health / Endothelial Function*;Diabetes / Insulin Resistance;Nutrition / Diet
Funding Source: Egg Nutrition Center
Funding Period: 2020-2021
Study Design: Randomized, single-blind, controlled, crossover trial

People who have diabetes, or are at risk for developing diabetes, have an increased likelihood of developing cardiovascular disease. Plant-based diets are recommended to reduce the risk of type 2 diabetes, as long as steps are taken to ensure adequate nutrient intake. Plant-based diets that exclude all foods from animal sources (i.e., vegan diets) require careful planning to ensure optimal intake of protein and other nutrients. Because eggs contain high quality protein and are rich in certain vitamins and minerals, adding eggs to a vegan diet could potentially improve diet quality. However, before recommending that adults at risk for type 2 diabetes add eggs to an otherwise vegan diet, it is important to first assess the effects of eating eggs on their risk for cardiovascular disease.

Further Study Details:

This study will assess the impact of including 2 eggs daily for 6 weeks in an otherwise vegan diet, compared with a vegan diet without eggs, on endothelial function (a measure of cardiovascular health), other cardio-metabolic risk factors, and dietary patterns in 35 adults who are at risk for type 2 diabetes. Each study participant will follow both diets (one with eggs, one without eggs) over the course of the study, but the order in which the diets are to be followed will be randomly assigned.


Men who are 25 to 75 years old, and women who have gone through menopause but are not on hormone replacement therapy. Those who qualify to be enrolled must be non-smokers, and have an increased risk for developing type 2 diabetes based on certain criteria that the study team is using.

Evaluation: At different time points, the study team will measure participants’ endothelial function, serum lipids, body composition, body weight, waist circumference, blood pressure, fasting insulin and fasting blood glucose, nutrient intake, and diet quality.

Changed at: 3/27/2020 2:58 PM Changed by:
Created at: 3/27/2020 2:58 PM Created by:

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