Tag: CORP** Pilot Study

Homeopathic Treatment for Attention Deficit-Hyperactivity Disorder

Title:Homeopathic Treatment for Attention Deficit-Hyperactivity Disorder
Status:Completed
Topic:CORP** Pilot Study
Funding Source:Centers for Disease Control and Prevention
Funding Period:2/03 – 8/03
Study Design:Randomized, Placebo-Controlled, Double-Blinded Pilot Study
Purpose:To determine the safety and efficacy (effectiveness) of homeopathy for the treatment of Attention Deficit-Hyperactivity Disorder (ADHD) in children ages 6-12 years.
Further Study Details:The study was conducted by Dr. Jennifer Jacobs at The Evergreen Center for Homeopathic Medicine in Edmonds, WA. Attention deficithyperactivity disorder is a prevalent condition affecting an estimated 4-12% of schoolaged children. The standard conventional treatments are effective at minimizing symptoms; however, these medications have some potential for addiction and abuse, and have the potential to produce notable side effects. It is believed that homeopathic medicine may offer the potential to be an effective adjuvant and perhaps alternative to conventional treatment. Forty-three children participated in this study and were assigned to one of two groups – individualized homeopathic remedy or placebo. All children received a standard homeopathic evaluation prior to beginning their treatment assignment. Outcomes of interest included attention and behavior as well as use/dose of conventional medications. The intervention lasted 18 weeks and children were evaluated at baseline (before treatment), 6, 12, and 18 weeks. The children were randomized to an intervention group or placebo group.
Findings:This pilot study did not provide evidence to support a therapeutic effect of individually selected homeopathic remedies in children with ADHD. A therapeutic effect of the homeopathic encounter was suggested but warrants further evaluation. Future studies should be carried out over a longer period of time and should include a control group that does not receive the homeopathic consultation. Comparison to conventional stimulant medication for ADHD also should be considered.
Eligibility:Children between the ages of 6-12 years with a diagnosis of ADHD.
Changed at:4/19/2018 6:16 AMChanged by:Lisa Seaberg
Created at:8/31/2010 10:31 AMCreated by:Griffin Hospital

A Yoga Intervention for Adults with Mild to Moderate Asthma

Title:A Yoga Intervention for Adults with Mild to Moderate Asthma
Status:Completed
Topic:CORP** Pilot Study
Funding Source:Centers for Disease Control and Prevention
Funding Period:10/01-3/03
Study Design:Randomized, Controlled, Double-Blind Pilot Study
Purpose:To determine the effectiveness and feasibility of a yoga and breathwork intervention in improving health status (clinical indices and quality of life) for adult patients with mild to moderate asthma.
Further Study Details:Although yoga has preliminary evidence associated with its effect on asthma, no previous studies used an active control group, as done in this study. A total of 62 men and women with mild to moderate asthma participated in this 16-week intervention. Participants were assigned to either the yoga group (active intervention) or stretching group (control); both groups attended structured classes for the first 4 weeks, then were instructed to continue the exercises learned in class for 3 more months at home. All participants were provided with an exercise mat, audiotape and print instructions. Assessments were conducted at baseline (before treatment), and at 4, 8, 12 and 16 weeks during the study.
Findings:This pilot study of Iyengar yoga did not demonstrate evidence of benefit in people with mild-to-moderate asthma. However, these results did not preclude a possible benefit of yoga in specific patient populations, in patients with greater severity of disease, or by practicing a different school of yoga. Circumstances under which yoga could be of benefit in asthma management remain to be determined.
Eligibility:Adult men and women with mild to moderate asthma.
Changed at:1/18/2011 6:53 AMChanged by:Judy Treu
Created at:8/31/2010 10:44 AMCreated by:Griffin Hospital

A Retrospective Cohort Study of Modified Citrus Pectin for the Prevention of Metastases in Prostate Cancer

Title:A Retrospective Cohort Study of Modified Citrus Pectin for the Prevention of Metastases in Prostate Cancer
Status:Completed
Topic:CORP** Pilot Study
Funding Source:Centers for Disease Control and Prevention
Funding Period:1/03-10/03
Study Design:Retrospective Cohort Study
Purpose:To assess the impact, by medical record review, of modified citrus pectin (MCP) use on the prevention of metastasis in men with prostate cancer.
Further Study Details:This study involved a chart review of prostate cancer patients. Of particular interest was the stage of prostate cancer, metastasis, types of therapy undergone, use of nutriceuticals and conventional medications. Data collected regarding MCP usage included the dose, frequency, and duration of MCP ingestion. This data was analyzed to determine what, if any, effect MCP has on the prevention of metastasis of prostate cancer.
Findings:Insufficient data prevented the completion of this pilot study as designed.
Eligibility:Prostate cancer patients treated at Southwestern Regional Medical Center, Midwestern Regional Medical Center, and Cancer Treatment Centers of America/Seattle.
Changed at:1/18/2011 6:50 AMChanged by:Judy Treu
Created at:8/31/2010 10:33 AMCreated by:Griffin Hospital

A Massage Therapy Intervention for Osteoarthritis of the Knee

Title:A Massage Therapy Intervention for Osteoarthritis of the Knee
Status:Completed
Topic:CORP** Pilot Study
Funding Source:Centers for Disease Control and Prevention
Funding Period:2/03 – 6/06
Study Design:Randomized, Controlled Clinical Trial
Purpose:To determine the effectiveness of massage therapy in improving pain and joint mobility for patients with osteoarthritis of the knee.
Further Study Details:The study was conducted by Dr. Adam Perlman at the Siegler Center for Integrative Medicine at St. Barnabus Medical Center, Livingston, NJ. Arthritis is a highly prevalent disease, and although massage therapy has been proven effective in other forms of rheumatism, no study has specifically evaluated the effectiveness of massage therapy for osteoarthritis. Approximately 60 men and women with a diagnosis of OA of the knee were assigned to one of two groups. The massage group received 8 weeks of massage, while the control group was “wait-listed” during which time they received their usual care. At the completion of the 8-week massage intervention, the control group also received the massage intervention. Outcomes of interest include pain and mobility measures assessed before, during, and after the intervention.
Findings:The group which received massage therapy demonstrated significant improvements in the WOMAC global scores, pain, stiffness, and physical function domains, and in the visual analog scale of pain assessment, range of motion in degrees, and time to walk 50 ft (15 m). This study demonstrated massage therapy to be efficacious in the treatment of OA of the knee. These findings are particularly relevant since pharmacological treatments often have undesirable side effects. Further study of cost effectiveness and duration of treatment effect is warranted.
Eligibility:Adult men and women with diagnosis of osteoarthritis of the knee.
Changed at:1/18/2011 6:52 AMChanged by:Judy Treu
Created at:8/31/2010 10:35 AMCreated by:Griffin Hospital