Cardiovascular diseases (CVDs) are disorders of the heart and blood vessels. Since symptoms often remain silent until a major health event occurs, it is important to detect and prevent CVDs at an early stage before symptoms occur. One non-invasive means measures the function of endothelial cells that line the inside of blood vessels and help them dilate properly as blood flows through them. Endothelial function is usually measured by a non-invasive ultrasound procedure that checks how well the brachial artery in the arm dilates as blood flows through it. This procedure works well, but requires highly skilled technicians and expensive equipment. This study compared a new automated machine (AngioDefenderTM) to brachial artery ultrasound imaging (BAUI) in measuring blood vessel function.
Further Study Details:
Other sites participating in this study included the Boston University School of Medicine, the Medical College of Wisconsin, and the University of Colorado.
Findings:
Data obtained from these studies will be used to refine the automated technology.
Eligibility:
Adults at least 18 years of age who might qualify to take part based on their overall health status, body mass index (BMI), arm circumference, blood pressure, blood cholesterol and glucose levels, absence of certain CVD clinical signs, absence of viral or bacterial infections, and ability to comply with study procedures.
Yale-Griffin Prevention Research Center